Active Ingredients

Vectra® 3D controls dangerous parasites three ways.

In insects, mimics the neurotransmitter acetylcholine, which activates nerve impulses at the synapse receptor.
Contrary to acetylcholine whose effects are terminated very fast, dinotefuran is not susceptible to synaptic enzymes. Dinotefuran binds permanently and causes continuous nerve stimulation.
Dinotefuran causes paralysis and death to insects.
Kills fleas by contact; ingestion is not required.
After application, this compound adheres to the skin surface and hair of dogs and puppies.
Does not bind to mammalian acetylcholine receptor sites.
Exclusive active to Ceva in the EU and US.

Extremely potent, long-lasting and photostable.
Targets the reproduction and development of insects such as fleas. Sterilises adult fleas, kills larvae and prevents emergence of new adults.
Mimics the growth hormone (Juvenile Hormone) regulating when the insect molts and moves to the next life stage.
Normally, the JH breaks down over time, allowing the molting, but Pyriproxyfen keeps the hormone level too high to allow the molt, and they eventually die.

Is a synthetic pyrethroid.
Repels and knock-down the parasites
Insecticide and acaricide which targets the nervous system of arthropods
During a nerve impulse, voltage-gated sodium channels open, causing depolarisation of the nerve.
Permethrin binds to this gate protein and prevents it from closing normally.
This causes repetitive activity in the sensory and motor pathways, causing tremors.
Parasites lose control of their nervous system, are unable to produce coordinated movement and die.